Transcriptomic aging clocks estimate biological age based on gene expression patterns. These clocks reflect age-related changes in transcriptional regulation across tissues. Transcriptomic aging clocks capture shifts in immune activity, metabolism, and stress response pathways. They provide insight into tissue-specific aging dynamics. Transcriptomic clocks are sensitive to environmental and lifestyle influences. Understanding transcriptomic aging clocks highlights gene regulation as a measurable dimension of biological aging.
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Kenneth R Pelletier, University of California School of Medicine, United States
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