This track examines how epigenetic changes contribute to aging and how reprogramming strategies may restore youthful function. Topics include DNA methylation, histone modifications, chromatin architecture, and non-coding RNAs as regulators of gene expression over the lifespan. Epigenetics and Reprogramming in Aging the session will discuss epigenetic clocks as quantitative measures of biological age, their development, validation, and clinical utility. Partial cellular reprogramming, transcription factor–based rejuvenation, and small molecule epigenetic modulators will be explored with attention to efficacy, specificity, and oncogenic risk. Emphasis will be placed on mechanistic studies, multi-omics integration, and translational work linking epigenetic remodeling to functional outcomes in tissues and organisms.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom