This Mitochondria, Metabolism and Redox Aging session addresses mitochondrial dysfunction, altered energy metabolism, and redox imbalance as central features of aging. Presentations will cover mitochondrial DNA mutations, dynamics (fission/fusion), mitophagy, and bioenergetic decline across organs. The role of nutrient sensing pathways, such as mTOR, AMPK, sirtuins, and insulin/IGF signaling, in modulating lifespan and healthspan will be highlighted. Oxidative stress, reactive oxygen species signaling, and antioxidant defense mechanisms will be discussed with emphasis on current evidence and controversies. The track welcomes basic, translational, and clinical studies investigating metabolic and mitochondrial-targeted interventions, including dietary restriction mimetics, NAD+ boosters, and metabolic reprogramming strategies in aging populations.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom