World Aging & Longevity Conference
October 08-10, 2026
Synaptic Aging
Synaptic aging describes age-associated changes in structure, function, and density of synaptic connections. Synapses are essential for communication between neurons and underlie learning and memory. With aging, synaptic plasticity declines, neurotransmitter release becomes less efficient, and synaptic proteins are altered. Reduced synaptic maintenance leads to weakened neural connectivity and slower information processing. Synaptic aging is influenced by oxidative stress, inflammation, and metabolic imbalance. Loss of synaptic integrity precedes neuronal loss and is strongly linked to cognitive decline. Understanding synaptic aging emphasizes preservation of synaptic function as a key strategy for maintaining cognitive health during aging.
Kenneth R Pelletier
University of California School of Medicine, United States
Thomas J Webster
Brown University, United States
Jason Beckwith
BioTalent, United Kingdom
Sergey Suchkov
N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Jose Cordeiro Mateo
International Longevity Summit, Spain
Ashot Khachatryan
National Academy of Sciences of the Republic of Armenia, Armenia
Utpol Das
University of Texas Medical Branch at Galveston, United StatesSubmit your abstract Today
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom