Supercentenarians are individuals who live beyond 110 years of age and represent the extreme end of human longevity. They are rare and provide exceptional insight into the limits of human lifespan. Supercentenarians often exhibit remarkable resistance to chronic diseases and maintain functional independence late into life. Biological studies suggest that supercentenarians may possess unique genetic and molecular features that protect against cellular damage and systemic decline. Their immune systems, metabolic regulation, and stress-response mechanisms appear particularly robust. Studying supercentenarians helps researchers understand the upper boundaries of human longevity and identify biological traits that promote extreme survival and healthspan.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom