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World Aging & Longevity Conference

October 08-10, 2026

Stress-Induced Senescence

Stress-Induced Senescence

Stress-induced senescence is triggered by cellular stressors independent of cell division, including oxidative stress, DNA damage, radiation, oncogene activation, and mitochondrial dysfunction. Unlike replicative senescence, this form can occur rapidly in both dividing and non-dividing cells. Stress-induced senescence acts as a protective response to prevent damaged cells from proliferating, thereby reducing cancer risk. However, persistent stress-induced senescence contributes to tissue dysfunction and chronic inflammation during aging. These senescent cells often display a strong SASP, amplifying inflammatory signaling and promoting aging in surrounding tissues. Stress-induced senescence links environmental exposures, metabolic imbalance, and lifestyle factors directly to biological aging, making it a key focus in preventive aging research.

Committee Members
Speaker at Geriatrics Conference - Kenneth R Pelletier

Kenneth R Pelletier

University of California School of Medicine, United States
Speaker at Aging Conferences - Thomas J Webster

Thomas J Webster

Brown University, United States
Speaker at Aging Conferences - Jason Beckwith

Jason Beckwith

BioTalent, United Kingdom
WALC 2026 Speakers
Speaker at Aging Conferences - Sergey Suchkov

Sergey Suchkov

N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Speaker at Geriatrics Conference - Jose Cordeiro Mateo

Jose Cordeiro Mateo

International Longevity Summit, Spain
Speaker at Aging Conferences - Ashot Khachatryan

Ashot Khachatryan

National Academy of Sciences of the Republic of Armenia, Armenia
Speaker at Aging Conferences - Utpol Das

Utpol Das

University of Texas Medical Branch at Galveston, United States
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