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World Aging & Longevity Conference

October 08-10, 2026

Stem Cell Niche Aging

Stem Cell Niche Aging

Stem cell niche aging refers to age-associated changes in the microenvironment that supports stem cell maintenance and function. The niche provides physical support, signaling cues, and metabolic regulation essential for stem cell behavior. With aging, niche composition and signaling become altered due to inflammation, fibrosis, vascular decline, and extracellular matrix remodeling. These changes impair stem cell self-renewal and differentiation, even when stem cells themselves remain viable. Stem cell niche aging contributes to reduced tissue regeneration and delayed repair. Understanding niche aging emphasizes that stem cell dysfunction arises from both intrinsic cellular changes and extrinsic environmental deterioration. Targeting niche integrity is critical for restoring regenerative capacity during aging.

Committee Members
Speaker at Geriatrics Conference - Kenneth R Pelletier

Kenneth R Pelletier

University of California School of Medicine, United States
Speaker at Aging Conferences - Thomas J Webster

Thomas J Webster

Brown University, United States
Speaker at Aging Conferences - Jason Beckwith

Jason Beckwith

BioTalent, United Kingdom
WALC 2026 Speakers
Speaker at Aging Conferences - Sergey Suchkov

Sergey Suchkov

N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Speaker at Geriatrics Conference - Jose Cordeiro Mateo

Jose Cordeiro Mateo

International Longevity Summit, Spain
Speaker at Aging Conferences - Ashot Khachatryan

Ashot Khachatryan

National Academy of Sciences of the Republic of Armenia, Armenia
Speaker at Aging Conferences - Utpol Das

Utpol Das

University of Texas Medical Branch at Galveston, United States

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