Sleep aging refers to age-related changes in sleep duration, architecture, and quality. Older individuals often experience reduced deep sleep, increased nighttime awakenings, and earlier sleep timing. These changes reflect alterations in circadian regulation, neural signaling, and hormonal control. Sleep aging affects memory consolidation, immune function, metabolic regulation, and emotional health. Chronic sleep disruption accelerates biological aging by increasing inflammation, oxidative stress, and metabolic imbalance. Sleep aging also reduces recovery capacity following physiological stress. Understanding sleep aging highlights sleep as a modifiable factor influencing healthspan, cognitive preservation, and systemic resilience throughout aging.
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Kenneth R Pelletier, University of California School of Medicine, United States
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