Redox imbalance aging refers to disruption of equilibrium between oxidant production and antioxidant defenses during aging. Healthy cells maintain redox balance to support signaling while limiting damage. With aging, increased oxidant generation and weakened antioxidant capacity shift cells toward oxidative stress. Redox imbalance aging alters signaling pathways, damages macromolecules, and impairs cellular adaptation. Persistent imbalance accelerates functional decline across tissues. Understanding redox imbalance aging emphasizes redox regulation as a central determinant of cellular resilience and aging biology.
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