Partial reprogramming aging involves transient activation of developmental programs to restore youthful cellular function without erasing cell identity. This approach rejuvenates epigenetic markers and improves tissue function while avoiding full dedifferentiation. Partial reprogramming targets aging-associated epigenetic drift and restores transcriptional stability. Studies show improvements in regenerative capacity and stress resistance. Partial reprogramming aging represents a promising strategy for functional rejuvenation while maintaining tissue integrity. Understanding this approach highlights epigenetic regulation as a reversible component of aging biology.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
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