Ovarian aging refers to age-associated decline in ovarian reserve, oocyte quality, and endocrine function. This process begins early in adulthood and accelerates over time. Ovarian aging leads to reduced fertility, altered hormone production, and eventual reproductive cessation. Declining estrogen levels influence bone density, cardiovascular health, metabolism, and brain function. Ovarian aging reflects cumulative cellular damage, mitochondrial dysfunction, and altered signaling within ovarian tissue. Understanding ovarian aging is essential for addressing reproductive health and broader systemic aging effects in females.
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