Organ system aging refers to cumulative decline in structure and function of entire physiological systems over time. Aging affects cardiovascular, musculoskeletal, nervous, immune, endocrine, and metabolic systems. Reduced reserve capacity and impaired adaptability characterize aging organ systems. Decline in one system often influences others, amplifying functional deterioration. Organ system aging results from integrated effects of cellular damage, stem cell decline, and impaired intercellular communication. Understanding organ system aging supports holistic approaches to aging intervention that target system integration rather than isolated organs.
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Kenneth R Pelletier, University of California School of Medicine, United States
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Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
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Arthur J Siegel, McLean Hospital, United States
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Narendra Kumar, HeartbeatsZ Academy, United Kingdom