Nuclear lamina aging describes deterioration of the nuclear lamina, a structural network supporting nuclear shape and chromatin organization. The nuclear lamina anchors chromatin and regulates gene expression. With aging, lamina integrity declines, leading to nuclear deformation, chromatin mislocalization, and transcriptional instability. Nuclear lamina aging disrupts genome organization and cellular stress responses. These changes contribute to cellular senescence, impaired repair, and tissue dysfunction. Nuclear lamina defects are associated with accelerated aging phenotypes. Studying nuclear lamina aging provides insight into how structural nuclear components influence longevity and cellular resilience.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom