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World Aging & Longevity Conference

October 08-10, 2026

Nuclear Lamina Aging

Nuclear Lamina Aging

Nuclear lamina aging describes deterioration of the nuclear lamina, a structural network supporting nuclear shape and chromatin organization. The nuclear lamina anchors chromatin and regulates gene expression. With aging, lamina integrity declines, leading to nuclear deformation, chromatin mislocalization, and transcriptional instability. Nuclear lamina aging disrupts genome organization and cellular stress responses. These changes contribute to cellular senescence, impaired repair, and tissue dysfunction. Nuclear lamina defects are associated with accelerated aging phenotypes. Studying nuclear lamina aging provides insight into how structural nuclear components influence longevity and cellular resilience.

Committee Members
Speaker at Geriatrics Conference - Kenneth R Pelletier

Kenneth R Pelletier

University of California School of Medicine, United States
Speaker at Aging Conferences - Thomas J Webster

Thomas J Webster

Brown University, United States
Speaker at Aging Conferences - Jason Beckwith

Jason Beckwith

BioTalent, United Kingdom
WALC 2026 Speakers
Speaker at Aging Conferences - Sergey Suchkov

Sergey Suchkov

N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Speaker at Geriatrics Conference - Jose Cordeiro Mateo

Jose Cordeiro Mateo

International Longevity Summit, Spain
Speaker at Aging Conferences - Ashot Khachatryan

Ashot Khachatryan

National Academy of Sciences of the Republic of Armenia, Armenia
Speaker at Aging Conferences - Utpol Das

Utpol Das

University of Texas Medical Branch at Galveston, United States

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