World Aging & Longevity Conference
October 08-10, 2026
NAD Metabolism Aging
NAD metabolism aging refers to age-associated changes in the synthesis, recycling, and utilization of nicotinamide adenine dinucleotide, a central coenzyme in cellular metabolism. NAD is essential for redox reactions, mitochondrial energy production, DNA repair, and regulation of stress-response enzymes. During aging, NAD metabolism becomes dysregulated due to reduced biosynthesis, increased consumption by repair enzymes, and chronic cellular stress. This imbalance compromises metabolic efficiency, impairs mitochondrial function, and weakens cellular maintenance systems. NAD metabolism aging affects multiple tissues, including muscle, brain, and immune cells, contributing to systemic functional decline. Understanding NAD metabolism aging provides insight into how metabolic failure accelerates biological aging and highlights metabolic restoration as a key strategy for promoting healthspan.
Kenneth R Pelletier
University of California School of Medicine, United States
Thomas J Webster
Brown University, United States
Jason Beckwith
BioTalent, United Kingdom
Sergey Suchkov
N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Jose Cordeiro Mateo
International Longevity Summit, Spain
Ashot Khachatryan
National Academy of Sciences of the Republic of Armenia, Armenia
Utpol Das
University of Texas Medical Branch at Galveston, United StatesSubmit your abstract Today
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom