Myelin degeneration aging refers to age-associated deterioration of myelin sheaths that insulate axons and facilitate efficient neural signaling. With aging, myelin maintenance and repair decline, leading to thinner or fragmented myelin. This degeneration slows nerve conduction and increases vulnerability to axonal damage. Myelin degeneration aging contributes to cognitive slowing, motor impairment, and reduced neural coordination. Inflammatory signaling and metabolic stress exacerbate myelin loss. Understanding myelin degeneration aging highlights importance of oligodendrocyte health and lipid metabolism in preserving neural communication.
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