World Aging & Longevity Conference
October 08-10, 2026
mTOR Signaling Aging
mTOR signaling aging refers to age-related changes in the mechanistic target of rapamycin pathway, a key regulator of cell growth, metabolism, and survival. This pathway integrates nutrient availability, energy status, and growth signals to control protein synthesis and autophagy. During aging, chronic activation of mTOR favors cellular growth over maintenance, leading to reduced autophagy, accumulation of damaged proteins, and impaired cellular homeostasis. Excessive mTOR activity is associated with accelerated aging and increased risk of cancer, neurodegeneration, and metabolic disorders. Suppression of mTOR signaling shifts cellular priorities toward repair, stress resistance, and metabolic efficiency. mTOR signaling aging represents a central mechanism linking nutrient sensing to lifespan regulation and remains a major focus in longevity research.
Kenneth R Pelletier
University of California School of Medicine, United States
Thomas J Webster
Brown University, United States
Jason Beckwith
BioTalent, United Kingdom
Sergey Suchkov
N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Jose Cordeiro Mateo
International Longevity Summit, Spain
Ashot Khachatryan
National Academy of Sciences of the Republic of Armenia, Armenia
Utpol Das
University of Texas Medical Branch at Galveston, United StatesSubmit your abstract Today
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom