Metabolomic aging refers to age-related alterations in small-molecule metabolites that reflect changes in cellular metabolism and physiological state. Aging affects energy production, lipid metabolism, amino acid balance, and redox status. Metabolomic profiles shift as mitochondrial efficiency declines and nutrient sensing becomes dysregulated. These changes influence inflammation, immune function, and tissue repair. Metabolomic aging captures systemic effects of aging across multiple organs. It provides an integrated snapshot of biological aging influenced by genetics, lifestyle, and environment. Studying metabolomic aging supports identification of metabolic biomarkers and pathways associated with healthspan and disease risk. Metabolomics offers a functional readout of aging processes at organismal scale.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom