Longevity genes are genetic factors that influence lifespan, healthspan, and resistance to age-related diseases. These genes regulate key biological processes such as DNA repair, stress resistance, metabolism, inflammation, and cellular maintenance. Variations in longevity genes can enhance an organism’s ability to cope with molecular damage and environmental stressors, thereby slowing biological aging. Longevity genes often act through conserved pathways that affect energy sensing, cellular repair, and survival mechanisms. Rather than determining lifespan alone, these genes interact with lifestyle and environmental factors to shape aging trajectories. Studying longevity genes provides insight into why individuals age at different rates and helps identify molecular targets for interventions aimed at extending healthy lifespan rather than simply increasing years lived.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom