Longevity assurance mechanisms are biological systems that protect against cumulative damage and maintain function over time. These mechanisms include DNA repair, proteostasis networks, antioxidant defenses, and immune surveillance. Longevity assurance mechanisms enhance stress tolerance and delay onset of dysfunction. Their efficiency determines resilience and aging rate. With advancing age, these mechanisms gradually decline, increasing vulnerability. Studying longevity assurance mechanisms reveals targets for interventions aimed at preserving cellular and systemic integrity. Understanding these mechanisms emphasizes maintenance and repair as central principles of longevity.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom