Inter organ communication aging describes age-related disruption in signaling between organs that coordinate metabolism, immunity, and stress responses. Organs communicate through hormones, cytokines, metabolites, and neural pathways. With aging, signaling becomes dysregulated, leading to poor coordination and loss of systemic balance. Impaired inter organ communication aging contributes to metabolic instability, inflammation, and reduced stress tolerance. Breakdown in organ crosstalk accelerates functional decline and disease development. Understanding inter organ communication aging highlights aging as a systems-level process requiring integrative intervention strategies.
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