HYBRID EVENT: Join us in person in Tokyo, Japan or attend virtually from anywhere.
World Aging & Longevity Conference
October 08-10, 2026
Insulin Signaling Aging
Insulin Signaling Aging
Insulin signaling aging describes progressive changes in insulin responsiveness and metabolic regulation over time. Aging is commonly associated with reduced insulin sensitivity, leading to impaired glucose handling and increased risk of metabolic disease. Dysregulated insulin signaling contributes to oxidative stress, inflammation, and altered nutrient sensing. Moderated insulin signaling has been linked to improved longevity and metabolic resilience in experimental models. Insulin signaling aging interacts closely with mTOR, AMPK, and FOXO pathways, influencing cellular maintenance and stress responses. Maintaining balanced insulin signaling is essential for metabolic stability and healthy aging across tissues.
Committee Members
Kenneth R Pelletier
University of California School of Medicine, United States
Thomas J Webster
Brown University, United States
Jason Beckwith
BioTalent, United Kingdom WALC 2026 Speakers
Sergey Suchkov
N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Jose Cordeiro Mateo
International Longevity Summit, Spain
Ashot Khachatryan
National Academy of Sciences of the Republic of Armenia, Armenia
Utpol Das
University of Texas Medical Branch at Galveston, United StatesSubmit your abstract Today
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom