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World Aging & Longevity Conference

October 08-10, 2026

Hematopoietic Stem Cell Aging

Hematopoietic Stem Cell Aging

Hematopoietic stem cell (HSC) aging affects the production of blood and immune cells throughout life. Aged HSCs show reduced self-renewal, impaired regenerative capacity, and altered lineage commitment. Aging skews HSC differentiation toward myeloid lineages, contributing to immunosenescence and chronic inflammation. Accumulated DNA damage and epigenetic changes compromise HSC function and increase the risk of hematological disorders. HSC aging plays a central role in declining immune competence and reduced resilience to infection in older individuals. Understanding HSC aging is critical for improving immune health and hematopoietic function during aging.

Committee Members
Speaker at Geriatrics Conference - Kenneth R Pelletier

Kenneth R Pelletier

University of California School of Medicine, United States
Speaker at Aging Conferences - Thomas J Webster

Thomas J Webster

Brown University, United States
Speaker at Aging Conferences - Jason Beckwith

Jason Beckwith

BioTalent, United Kingdom
WALC 2026 Speakers
Speaker at Aging Conferences - Sergey Suchkov

Sergey Suchkov

N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Speaker at Geriatrics Conference - Jose Cordeiro Mateo

Jose Cordeiro Mateo

International Longevity Summit, Spain
Speaker at Aging Conferences - Ashot Khachatryan

Ashot Khachatryan

National Academy of Sciences of the Republic of Armenia, Armenia
Speaker at Aging Conferences - Utpol Das

Utpol Das

University of Texas Medical Branch at Galveston, United States
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