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World Aging & Longevity Conference

October 08-10, 2026

Genomic Instability Aging

Genomic Instability Aging

Genomic instability aging refers to the progressive accumulation of genetic alterations over time, including mutations, chromosomal aberrations, and structural DNA changes. Aging cells experience increased genomic instability due to continuous exposure to DNA-damaging agents and declining genome maintenance mechanisms. Oxidative stress, replication errors, and environmental insults contribute to persistent DNA lesions. As genomic integrity deteriorates, cells become more prone to dysfunction, senescence, apoptosis, or malignant transformation. Genomic instability is a major driver of aging phenotypes and age-related diseases, particularly cancer. Preserving genome stability is essential for long-term cellular function and organismal health, making it a fundamental aspect of aging biology.

Committee Members
Speaker at Geriatrics Conference - Kenneth R Pelletier

Kenneth R Pelletier

University of California School of Medicine, United States
Speaker at Aging Conferences - Thomas J Webster

Thomas J Webster

Brown University, United States
Speaker at Aging Conferences - Jason Beckwith

Jason Beckwith

BioTalent, United Kingdom
WALC 2026 Speakers
Speaker at Aging Conferences - Sergey Suchkov

Sergey Suchkov

N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Speaker at Geriatrics Conference - Jose Cordeiro Mateo

Jose Cordeiro Mateo

International Longevity Summit, Spain
Speaker at Aging Conferences - Ashot Khachatryan

Ashot Khachatryan

National Academy of Sciences of the Republic of Armenia, Armenia
Speaker at Aging Conferences - Utpol Das

Utpol Das

University of Texas Medical Branch at Galveston, United States
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