Genetic determinants of aging refer to inherited variants that influence biological aging rate and disease vulnerability. These genes regulate metabolism, stress response, DNA repair, inflammation, and cellular maintenance. Genetic determinants do not act alone but interact with environmental and lifestyle factors. Certain variants support longevity through enhanced resilience and repair capacity. Genetic determinants of aging explain part of interindividual variability in lifespan and healthspan. Understanding genetic contributions enables identification of conserved aging pathways and personalized intervention approaches. This knowledge informs precision aging strategies while recognizing limits of genetic influence.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom