Frailty syndrome is a clinical condition characterized by reduced physiological reserve and increased vulnerability to stressors. It manifests as weakness, low energy, slowed movement, and reduced resistance to illness or injury. Frailty results from cumulative decline across multiple systems, including musculoskeletal, metabolic, immune, and neurological systems. Frailty syndrome increases risk of falls, disability, hospitalization, and mortality. It represents a distinct aging phenotype rather than normal aging alone. Early identification of frailty enables interventions that preserve function and improve outcomes. Frailty syndrome is a key focus in aging research and geriatric care.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom