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World Aging & Longevity Conference

October 08-10, 2026

Extracellular Matrix Aging

Extracellular Matrix Aging

Extracellular matrix aging refers to progressive deterioration of the structural network that supports cells and tissues. The extracellular matrix provides mechanical strength, elasticity, and signaling cues essential for tissue function. With aging, matrix composition changes due to reduced synthesis, increased degradation, and altered organization of structural proteins. These changes impair tissue resilience and disrupt cell–matrix interactions. Extracellular matrix aging contributes to tissue stiffness, fibrosis, and impaired regeneration. Accumulation of damaged matrix components further amplifies inflammation and cellular stress. Understanding extracellular matrix aging highlights how structural tissue scaffolds influence functional decline across organs during aging.

Committee Members
Speaker at Geriatrics Conference - Kenneth R Pelletier

Kenneth R Pelletier

University of California School of Medicine, United States
Speaker at Aging Conferences - Thomas J Webster

Thomas J Webster

Brown University, United States
Speaker at Aging Conferences - Jason Beckwith

Jason Beckwith

BioTalent, United Kingdom
WALC 2026 Speakers
Speaker at Aging Conferences - Sergey Suchkov

Sergey Suchkov

N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Speaker at Geriatrics Conference - Jose Cordeiro Mateo

Jose Cordeiro Mateo

International Longevity Summit, Spain
Speaker at Aging Conferences - Ashot Khachatryan

Ashot Khachatryan

National Academy of Sciences of the Republic of Armenia, Armenia
Speaker at Aging Conferences - Utpol Das

Utpol Das

University of Texas Medical Branch at Galveston, United States
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