An epigenetic clock is a mathematical model that estimates biological age based on specific DNA methylation patterns across the genome. These clocks provide highly accurate predictions of age and are strong predictors of morbidity, mortality, and functional decline. Accelerated epigenetic age—when epigenetic age exceeds chronological age—is associated with increased risk of cardiovascular disease, cancer, neurodegeneration, and frailty. Epigenetic clocks are widely used in aging research to evaluate interventions, lifestyle effects, and disease progression. Recent developments include tissue-specific clocks and clocks that predict healthspan rather than age alone. Epigenetic clocks have become essential tools in longevity science, enabling objective measurement of aging dynamics and intervention efficacy.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
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Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
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Narendra Kumar, HeartbeatsZ Academy, United Kingdom