Drug repurposing aging refers to the strategic use of existing approved drugs to target biological aging mechanisms. This approach leverages known safety profiles and clinical data to accelerate translation into aging interventions. Many drugs developed for metabolic, cardiovascular, or inflammatory conditions influence core aging pathways such as nutrient sensing, mitochondrial function, and cellular stress responses. Drug repurposing aging focuses on modifying disease risk and functional decline by acting upstream at shared biological mechanisms. This strategy reduces cost, development time, and regulatory barriers compared to novel drug discovery. Drug repurposing aging represents a pragmatic bridge between aging biology research and clinical application. Understanding this approach highlights efficiency and translational feasibility in advancing geroscience-based therapies.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom