Determinants of human longevity encompass genetic variation, biological aging mechanisms, lifestyle behaviors, and social environment. Human longevity reflects complex interactions between inherited traits and lifelong exposures. Factors such as metabolic regulation, immune competence, cardiovascular health, and stress adaptation strongly influence survival. Early life conditions and cumulative lifestyle patterns shape long-term aging trajectories. Determinants of human longevity explain differences in lifespan among populations and individuals. Understanding these determinants supports development of personalized longevity strategies. This framework emphasizes prevention, resilience, and functional preservation rather than disease-centered survival.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom