Cytokine dysregulation aging describes imbalance in production, timing, and regulation of cytokine signaling with age. Aging disrupts coordination between pro-inflammatory and anti-inflammatory cytokines. This imbalance impairs immune communication and tissue repair. Dysregulated cytokine networks promote chronic inflammation while weakening effective immune responses. Cytokine dysregulation aging affects metabolism, vascular function, and neural health. It also interferes with immune tolerance mechanisms. Understanding cytokine dysregulation aging provides insight into how immune signaling noise accelerates functional decline and disease susceptibility.
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