Compression of morbidity refers to the concept of reducing the period of illness, disability, and functional impairment toward the end of life. Rather than extending lifespan with prolonged disease, compression of morbidity aims to maintain health and function until late life, followed by a relatively short period of decline. This concept is central to healthy aging and longevity science. Compression of morbidity depends on delaying onset of chronic diseases and slowing functional deterioration. Biological aging processes strongly influence whether morbidity is compressed or extended. Achieving compression of morbidity reduces healthcare burden, improves quality of life, and supports independence in older adults. Research in this area focuses on interventions that preserve physiological resilience, metabolic balance, and cognitive function across the lifespan. Compression of morbidity reframes aging success in terms of quality rather than duration alone.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom