Chronic low grade inflammation aging describes persistent, systemic inflammatory activation that develops with advancing age. This condition arises from immune dysregulation, cellular senescence, mitochondrial dysfunction, and impaired clearance of damaged cells. Chronic inflammation accelerates tissue degeneration and disrupts metabolic homeostasis. It contributes to cardiovascular disease, neurodegeneration, frailty, and cancer risk. Chronic low grade inflammation aging reflects failure of immune resolution mechanisms and plays a central role in biological aging. Targeting inflammatory processes is essential for promoting healthy aging and reducing disease burden.
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