World Aging & Longevity Conference
October 08-10, 2026
ATM ATR Aging
ATM ATR aging refers to age-associated alterations in activity of ATM and ATR kinases, key sensors of DNA damage. These kinases detect DNA strand breaks and replication stress, initiating signaling cascades that coordinate repair and cell cycle control. With aging, increased DNA damage leads to sustained activation of ATM and ATR pathways. While this response preserves genomic integrity, chronic signaling contributes to prolonged cell cycle arrest and senescence. ATM ATR aging is associated with impaired stem cell function, reduced tissue regeneration, and increased inflammation. Dysregulation of these kinases compromises balance between repair and renewal. Studying ATM ATR aging helps explain how persistent DNA damage signaling contributes to aging phenotypes and functional decline.
Kenneth R Pelletier
University of California School of Medicine, United States
Thomas J Webster
Brown University, United States
Jason Beckwith
BioTalent, United Kingdom
Sergey Suchkov
N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Jose Cordeiro Mateo
International Longevity Summit, Spain
Ashot Khachatryan
National Academy of Sciences of the Republic of Armenia, Armenia
Utpol Das
University of Texas Medical Branch at Galveston, United StatesSubmit your abstract Today
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom