Aging signaling pathways are molecular communication routes that regulate growth, maintenance, stress response, and survival during aging. With age, signaling balance shifts away from repair toward damage accumulation and inflammation. Dysregulation of signaling pathways disrupts cellular coordination and tissue homeostasis. Aging signaling pathways integrate metabolic status, immune activity, and stress signals. Altered signaling contributes to cellular senescence, stem cell dysfunction, and metabolic decline. Studying aging signaling pathways provides insight into conserved mechanisms that influence lifespan and healthspan. These pathways represent critical targets for interventions aimed at slowing biological aging.
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