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World Aging & Longevity Conference

October 08-10, 2026

Aging Mechanisms

Aging Mechanisms

Aging mechanisms are the underlying biological processes that drive aging at multiple levels of organization. Widely recognized mechanisms include genomic instability, telomere shortening, epigenetic alterations, mitochondrial dysfunction, cellular senescence, and dysregulated nutrient sensing. These mechanisms interact in complex networks, amplifying age-related damage and functional decline. Aging mechanisms are highly conserved across species, suggesting shared evolutionary origins. Studying these mechanisms has enabled the identification of potential intervention targets, such as mTOR inhibition, caloric restriction mimetics, and senolytic therapies. Understanding aging mechanisms is fundamental to shifting medicine from disease treatment to aging intervention and prevention.

Committee Members
Speaker at Geriatrics Conference - Kenneth R Pelletier

Kenneth R Pelletier

University of California School of Medicine, United States
Speaker at Aging Conferences - Thomas J Webster

Thomas J Webster

Brown University, United States
Speaker at Aging Conferences - Jason Beckwith

Jason Beckwith

BioTalent, United Kingdom
WALC 2026 Speakers
Speaker at Aging Conferences - Sergey Suchkov

Sergey Suchkov

N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Speaker at Geriatrics Conference - Jose Cordeiro Mateo

Jose Cordeiro Mateo

International Longevity Summit, Spain
Speaker at Aging Conferences - Ashot Khachatryan

Ashot Khachatryan

National Academy of Sciences of the Republic of Armenia, Armenia
Speaker at Aging Conferences - Utpol Das

Utpol Das

University of Texas Medical Branch at Galveston, United States

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