Aging and obesity interact through changes in body composition, metabolism, and energy regulation. Aging is associated with increased fat accumulation and reduced lean muscle mass, even without significant weight gain. Obesity amplifies aging-related inflammation, insulin resistance, and metabolic dysfunction. Excess adipose tissue disrupts hormonal signaling and increases oxidative stress. Aging and obesity together increase risk of chronic disease, frailty, and reduced mobility. This interaction accelerates biological aging and compromises functional independence. Addressing obesity during aging is critical for preserving metabolic health, mobility, and overall quality of life.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
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Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom