Aging and energy homeostasis refers to progressive imbalance between energy intake, storage, and expenditure during aging. Energy homeostasis is regulated by central and peripheral signaling systems that coordinate metabolism, appetite, and energy utilization. With aging, these systems lose precision due to hormonal shifts, mitochondrial decline, and impaired nutrient sensing. Reduced energy efficiency limits cellular repair and stress adaptation. Aging and energy homeostasis disruption contributes to fatigue, metabolic disease, and functional decline. Altered energy balance also influences immune function and tissue regeneration. Understanding energy homeostasis aging highlights metabolism as a foundational regulator of biological aging and healthspan maintenance.
Title : Change your genes – Change your life: Epigenetics of longevity
Kenneth R Pelletier, University of California School of Medicine, United States
Title : Improving mobility and health in over 45,000 humans using nanomedicine
Thomas J Webster, Brown University, United States
Title : An introduction to alchemical facial acupuncture: Sparking the shen
Mary Elizabeth Wakefield, Chi-Akra Center for Ageless Aging, United States
Title : Decoding the secret of longevity through big data: Noncoding RNAs—not proteins—drive animal lifespan evolution
Anyou Wang, DIFIBER LLC, United States
Title : Aspirin guided by coronary artery calcium scoring for primary prevention in persons with subclinical coronary heart disease
Arthur J Siegel, McLean Hospital, United States
Title : When BMI misleads: Integrating body composition, biomarkers, and personalized interventions for cardiometabolic healthspan in aging Asian and European cohorts
Narendra Kumar, HeartbeatsZ Academy, United Kingdom